PEOPLE
WANG Yi 王一
WANG Yi / Professor
PHONE: (852) 3943 6355
EMAIL: yiwang@cuhk.edu.hk
OFFICE: Room 208, 2/F, Science Centre North Block
ORCID: 0000-0002-4174-8790
Education
- Postdoctoral Associate, Howard Hughes Medical Institute, University of California, San Diego, 2009-2012
- PhD, Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, 2003-2008
- BS, Biology (major) and Computer Science (minor), Zhejiang University, 1999-2003
Position
- 2025-now, Professor, Department of Physics, The Chinese University of Hong Kong, Hong Kong
- 2018-2025, Associate Professor, Department of Physics, The Chinese University of Hong Kong, Hong Kong
- 2012-2018, Assistant Professor, Department of Physics, The Chinese University of Hong Kong, Hong Kong
Research Interests
- Computational biophysics:
- Molecular simulations of protein conformations and dynamics
- Interactions of small molecules and nanoparticles with lipid membranes
- Structural and dynamic properties of hydrogels and coacervates
Selected Recent Publications
- Y. Qi, L.Y. Fung, C. Chipot*, Y. Wang*, Probing the Orientation and Membrane Permeation of Rhodamine Voltage Reporters through Molecular Simulations and Free Energy Calculations, Journal of Materials Chemistry B, 13:2015 – 2028, 2025.
- Y. Gou, T. Li, Y. Wang*, Active-site oxygen accessibility and catalytic loop dynamics of plant aromatic amino acid decarboxylases from molecular simulations, Biochemistry, 63:1980-1990, 2024.
- M. P. Torrens-Spence, J. O. Matos, T. Li, D. W. Kastner, C. Y. Kim, Z. Wang, C. M. Glinkerman, J. Sherk, H. J. Kulik , Y. Wang , J.-K. Weng, Mechanistic basis for the emergence of EPS1 as a catalyst in salicylic acid biosynthesis of Brassicaceae, Nature Communications, 15:10356, 2024.
- Y. Bo, T. Li, B. Yang, S. Chen, J. Zhao, P. Zhao, K. Zhang, Y. Wang*, Z. Wang*, L. Bian*, Surface hydrophobization of hydrogels via interface dynamics-induced network reconfiguration, Nature Communications, 15:239, 2024.
- B. Yang, K. Wei, C. Loebel, K. Zhang, Q. Feng, R. Li, D. S-h Wong, X. Xu, C. Lau, X. Chen, P. Zhao, C. Yin, J. A. Burdick, Y. Wang*, L. Bian*. Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics. Nature Communications, 12:3514, 2021.
Open Positions
Positions open for highly motivated undergrad, graduate and postdocs. Candidates interested in studying biomolecules using computational biophysics approaches are welcome to email yiwang@cuhk.edu.hk. Background in biophysics and/or programing is preferable but not required.